SENP1 antibody
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935106861
info@markelab.com
name
SENP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07712
tested applications
ELISA, IHC, WB
Description
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1(PubMed:25406032).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SUMO1/sentrin specific peptidase 1 (SENP1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 73 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9P0U3 |
| Gene ID | 29843 |
| Alias | Sentrin-specific protease 1,Sentrin/SUMO-specific protease SENP1,SENP1 |
| Background | Antibody anti-SENP1 |
| Status | RUO |
| Note | Mol. Weight 73 kDa |
Descripción
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