DHCR24 antibody
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 24-dehydrocholesterol reductase (DHCR24) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15392 |
| Alias | Delta(24)-sterol reductase,24-dehydrocholesterol reductase,3-beta-hydroxysterol Delta-24-reductase,Diminuto/dwarf1 homolog,Seladin-1,DHCR24,KIAA0018 |
| Background | Antibody anti-DHCR24 |
| Status | RUO |
| Note | Mol. Weight 60 kDa |
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24-Dehydrocholesterol Reductase (DHCR24) Antibody
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24-Dehydrocholesterol Reductase (DHCR24) Antibody
DHCR24 is a flavin adenine dinucleotide (FAD) dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
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