SEC13 antibody
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Description
Functions as a component of the nuclear pore complex(NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway. Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream and is regulated by amino acid sensors like SESN2(Probable).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SEC13 homolog (SEC13) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 36 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P55735 |
| Gene ID | 6396 |
| Alias | Protein SEC13 homolog,GATOR2 complex protein SEC13,SEC13-like protein 1,SEC13-related protein,SEC13,D3S1231E,SEC13A,SEC13L1,SEC13R |
| Background | Antibody anti-SEC13 |
| Status | RUO |
| Note | Mol. Weight 36 kDa |
Descripción
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