SDHA antibody

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935106861
info@markelab.com
name
SDHA antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07669
tested applications
ELISA, WB, IHC, IF
Description
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 70 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P31040 |
Gene ID | 6389 |
Alias | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial,Flavoprotein subunit of complex II (Fp),SDHA,SDH2,SDHF |
Background | Antibody anti-SDHA |
Status | RUO |
Note | Mol. Weight 70 kDa |
Descripción
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This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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