SCP2 antibody

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935106861
info@markelab.com
name
SCP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07654
tested applications
ELISA, WB

Description

Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
sterol carrier protein 2 (SCP2)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
13-15 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P22307
Gene ID
6342
Alias
Sterol carrier protein 2 (SCP-2),Acetyl-CoA C-myristoyltransferase,Non-specific lipid-transfer protein (NSL-TP),Propanoyl-CoA C-acyltransferase,SCP-2/3-oxoacyl-CoA thiolase,SCP-2/thiolase,SCP-chi,SCPX,Sterol carrier protein X (SCP-X),SCP2
Background
Antibody anti-SCP2
Status
RUO
Note
Mol. Weight 13-15 kDa

Descripción

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SCP2 antibody

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

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