SCN5A antibody
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Description
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | sodium channel, voltage-gated, type V, alpha subunit (SCN5A) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 227 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q14524 |
| Gene ID | 6331 |
| Alias | Sodium channel protein type 5 subunit alpha,Sodium channel protein cardiac muscle subunit alpha,Sodium channel protein type V subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.5,hH1,SCN5A |
| Background | Antibody anti-SCN5A |
| Status | RUO |
| Note | Mol. Weight 227 kDa |
Descripción
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