SCD antibody
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Description
Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates(PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA(PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids(PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation(By similarity). Plays an important role in body energy homeostasis(By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | stearoyl-CoA desaturase(delta-9-desaturase) (SCD) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 40 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O00767 |
| Gene ID | 6319 |
| Alias | Stearoyl-CoA desaturase (hSCD1),Acyl-CoA desaturase,Delta(9)-desaturase (Delta-9 desaturase),Fatty acid desaturase,SCD,FADS5,SCD1,SCDOS |
| Background | Antibody anti-SCD |
| Status | RUO |
| Note | Mol. Weight 40 kDa |
Descripción
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SCD antibody
Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates(PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA(PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids(PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation(By similarity). Plays an important role in body energy homeostasis(By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides(By similarity).
Ver Producto