SCARA5 antibody
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Description
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain(FTL) compared to heavy chain(FTH1)(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | scavenger receptor class A, member 5(putative) (SCARA5) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 43 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q6ZMJ2 |
| Gene ID | 286133 |
| Alias | Scavenger receptor class A member 5,Scavenger receptor hlg,SCARA5 |
| Background | Antibody anti-SCARA5 |
| Status | RUO |
| Note | Mol. Weight 43 kDa |
Descripción
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