SAMHD1 antibody
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935106861
info@markelab.com
name
SAMHD1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07592
tested applications
ELISA, WB, IHC, IP, FC
Description
Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SAM domain and HD domain 1 (SAMHD1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 64-72 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y3Z3 |
| Gene ID | 25939 |
| Alias | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase),Dendritic cell-derived IFNG-induced protein (DCIP),Monocyte protein 5 (MOP-5),SAM domain and HD domain-containing protein 1 (hSAMHD1),SAMHD1,MOP5 |
| Background | Antibody anti-SAMHD1 |
| Status | RUO |
| Note | Mol. Weight 64-72 kDa |
Descripción
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