RRM1 antibody

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935106861
info@markelab.com
name
RRM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07494
tested applications
ELISA, WB, IHC, IF, IP

Description

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ribonucleotide reductase M1 (RRM1)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:1000-1:4000; IF: 1:20-1:200
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
1F8
Observed MW
90 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Protein A+G purification
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P23921
Gene ID
6240
Alias
Ribonucleoside-diphosphate reductase large subunit,Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase large subunit,RRM1,RR1
Background
Antibody anti-RRM1
Status
RUO
Note
Mol. Weight 90 kDa

Descripción

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This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.

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RRM1 antibody

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

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