RNF7 antibody
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Description
Probable component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ring finger protein 7 (RNF7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 13 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UBF6 |
| Gene ID | 9616 |
| Alias | RING-box protein 2 (Rbx2),CKII beta-binding protein 1 (CKBBP1),RING finger protein 7,Regulator of cullins 2,Sensitive to apoptosis gene protein,RNF7,RBX2,ROC2,SAG |
| Background | Antibody anti-RNF7 |
| Status | RUO |
| Note | Mol. Weight 13 kDa |
Descripción
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