RNF213 antibody
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935106861
info@markelab.com
name
RNF213 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07351
tested applications
ELISA, IHC
Description
E3 ubiquitin-protein ligase involved in angiogenesis(PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression(PubMed:26766444). Also has ATPase activity(PubMed:24658080, PubMed:26126547).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ring finger protein 213 (RNF213) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q63HN8 |
| Gene ID | 57674 |
| Alias | E3 ubiquitin-protein ligase RNF213,ALK lymphoma oligomerization partner on chromosome 17,E3 ubiquitin-lipopolysaccharide ligase RNF213,Mysterin,RING finger protein 213,RNF213,ALO17,C17orf27,KIAA1554,KIAA1618,MYSTR |
| Background | Antibody anti-RNF213 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
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RNF213 antibody
E3 ubiquitin-protein ligase involved in angiogenesis(PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression(PubMed:26766444). Also has ATPase activity(PubMed:24658080, PubMed:26126547).
Ver Producto