RHOA antibody

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935106861
info@markelab.com
name
RHOA antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07281
tested applications
ELISA, WB, IHC
Description
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | ras homolog gene family, member A (RHOA) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 21 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P61586 |
Gene ID | 387 |
Alias | Transforming protein RhoA,Rho cDNA clone 12 (h12),RHOA,ARH12,ARHA,RHO12 |
Background | Antibody anti-RHOA |
Status | RUO |
Note | Mol. Weight 21 kDa |
Descripción
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RHOA antibody
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Ver Producto