RFC5 antibody
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Description
This gene encodes the smallest subunit of the replication factor C complex, which consists of five distinct subunits (140, 40, 38, 37, and 36 kDa) and is required for DNA replication. This subunit interacts with the C-terminal region of proliferating cell nuclear antigen and is required to open and load proliferating cell nuclear antigen onto DNA during S phase. It is a member of the AAA+ (ATPases associated with various cellular activities) ATPase family and forms a core complex with the 38 and 40 kDa subunits that possesses DNA-dependent ATPase activity. A related pseudogene has been identified on chromosome 9. Alternative splicing results in multiple transcript variants.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | replication factor C (activator 1) 5, 36.5kDa (RFC5) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 38 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P40937 |
| Gene ID | 5985 |
| Alias | Replication factor C subunit 5,Activator 1 36 kDa subunit (A1 36 kDa subunit),Activator 1 subunit 5,Replication factor C 36 kDa subunit (RF-C 36 kDa subunit, RFC36),RFC5 |
| Background | Antibody anti-RFC5 |
| Status | RUO |
| Note | Mol. Weight 38 kDa |
Descripción
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