RBM14 antibody
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Description
Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1(PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex(which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ(PubMed:25385835).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RNA binding motif protein 14 (RBM14) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70-75 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96PK6 |
| Gene ID | 10432 |
| Alias | RNA-binding protein 14,Paraspeckle protein 2 (PSP2),RNA-binding motif protein 14,RRM-containing coactivator activator/modulator,Synaptotagmin-interacting protein (SYT-interacting protein),RBM14,SIP |
| Background | Antibody anti-RBM14 |
| Status | RUO |
| Note | Mol. Weight 70-75 kDa |
Descripción
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