RAPSN antibody
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Description
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | receptor-associated protein of the synapse (RAPSN) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 43 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13702 |
| Gene ID | 5913 |
| Alias | 43 kDa receptor-associated protein of the synapse (RAPsyn),43 kDa postsynaptic protein,Acetylcholine receptor-associated 43 kDa protein,RING finger protein 205,RAPSN,RNF205 |
| Background | Antibody anti-RAPSN |
| Status | RUO |
| Note | Mol. Weight 43 kDa |
Descripción
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