RAD18 antibody
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Description
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAD18 homolog (RAD18) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 80 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NS91 |
| Gene ID | 56852 |
| Alias | E3 ubiquitin-protein ligase RAD18,Postreplication repair protein RAD18 (hHR18, hRAD18),RING finger protein 73,RING-type E3 ubiquitin transferase RAD18,RAD18,RNF73 |
| Background | Antibody anti-RAD18 |
| Status | RUO |
| Note | Mol. Weight 80 kDa |
Descripción
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