RACGAP1 antibody

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935106861
info@markelab.com
name
RACGAP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07070
tested applications
ELISA, IHC, IF, WB, IP

Description

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP(GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Rac GTPase activating protein 1 (RACGAP1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
71 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC, IF, WB, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9H0H5
Gene ID
29127
Alias
Rac GTPase-activating protein 1,Male germ cell RacGap (MgcRacGAP),Protein CYK4 homolog (CYK4, HsCYK-4),RACGAP1,KIAA1478,MGCRACGAP
Background
Antibody anti-RACGAP1
Status
RUO
Note
Mol. Weight 71 kDa

Descripción

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