RAB9A antibody
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935106861
info@markelab.com
name
RAB9A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07048
tested applications
ELISA, WB, IHC
Description
Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB9A, member RAS oncogene family (RAB9A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 23 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P51151 |
| Gene ID | 9367 |
| Alias | RAB9,Ras-related protein Rab-9A |
| Background | Antibody anti-RAB9A |
| Status | RUO |
| Note | Mol. Weight 23 kDa |
Descripción
RAB9A, member RAS oncogene family (RAB9A) is a GTPase that plays a key role in regulating vesicle transport between the late endosomes and the trans-Golgi network RAB9A is essential for the sorting and recycling of internalized proteins and lipids, particularly in the process of transporting cargo from the endosomes to the Golgi apparatus for further processing or secretion It is involved in the maintenance of cellular homeostasis by regulating the proper trafficking and degradation of internalized material In addition to its role in vesicular trafficking, RAB9A has been implicated in regulating cellular signaling pathways that influence immune responses, receptor recycling, and the dynamics of intracellular communication Alterations in RAB9A’s function are linked to various diseases, including cancer and neurodegenerative disorders, where disrupted vesicular trafficking leads to abnormal cell proliferation, tumor progression, and defective cellular waste clearance
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RAB9A antibody
Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
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