RAB6B antibody
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935106861
info@markelab.com
name
RAB6B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07042
tested applications
ELISA, WB, IHC, IF, IP
Description
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB6B, member RAS oncogene family (RAB6B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 24 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NRW1 |
| Gene ID | 51560 |
| Alias | Ras-related protein Rab-6B |
| Background | Antibody anti-RAB6B |
| Status | RUO |
| Note | Mol. Weight 24 kDa |
Descripción
RAB6B, member RAS oncogene family (RAB6B) is a small GTPase involved in regulating intracellular vesicle trafficking, particularly in the post-Golgi network RAB6B is essential for maintaining the proper organization of the Golgi apparatus and controlling vesicle transport between the Golgi and other cellular compartments It is involved in processes like protein sorting, secretion, and recycling, playing a crucial role in the movement of proteins, lipids, and other macromolecules within the cell Additionally, RAB6B is implicated in the regulation of mitosis, where it influences the dynamics of microtubules and membrane fusion during cell division Disruptions in RAB6B function have been associated with several types of cancer, where altered vesicular trafficking contributes to tumor progression, metastasis, and chemotherapy resistance Furthermore, RAB6B also participates in regulating immune responses by controlling the trafficking of immune receptors and cytokines
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