RAB3A-specific antibody

Product specifications

Primary Antibodies

RAB3A, member RAS oncogene family (RAB3A)

Rabbit

Human, Mouse, Rat

WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100

polyclonal

Unconjugated

IgG

25 kDa

≥95% as determined by SDS-PAGE

Immunogen affinity purified

100µg

liquid

ELISA, WB, IF, IHC

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

P20336

Ras-related protein Rab-3A,RAS-associated protein RAB3A

Antibody anti-RAB3A

RUO

Mol. Weight 25 kDa

RAB3A, member RAS oncogene family (RAB3A) is another small GTPase that is primarily involved in regulating vesicular trafficking, particularly in neurons and endocrine cells RAB3A plays a pivotal role in the regulated release of neurotransmitters and hormones through its involvement in synaptic vesicle recycling and exocytosis It is essential for the proper functioning of synapses, where it helps control the fusion of synaptic vesicles with the plasma membrane, allowing for neurotransmitter release and signal transmission between neurons In addition to its function in neurotransmission, RAB3A is also involved in insulin secretion in pancreatic beta cells Dysregulation of RAB3A is associated with neurological disorders, such as epilepsy and neurodegenerative diseases, as well as metabolic disorders like diabetes, where impaired vesicle trafficking and hormone release contribute to disease progression Understanding RAB3A’s role in cellular transport and neurotransmission is critical for developing therapeutic strategies for neurological and metabolic diseases

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