PUF60 antibody
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Description
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | poly-U binding splicing factor 60KDa (PUF60) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:20 - 1:50 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 65 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UHX1 |
| Gene ID | 22827 |
| Alias | Poly(U)-binding-splicing factor PUF60,60 kDa poly(U)-binding-splicing factor,FUSE-binding protein-interacting repressor (FBP-interacting repressor),Ro-binding protein 1 (RoBP1),Siah-binding protein 1 (Siah-BP1),PUF60,FIR,ROBPI,SIAHBP1 |
| Background | Antibody anti-PUF60 |
| Status | RUO |
| Note | Mol. Weight 65 kDa |
Descripción
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