anti- PTPRCAP / CD45AP antibody
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935106861
info@markelab.com
name
anti- PTPRCAP / CD45AP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06943
tested applications
ELISA, WB, IHC
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein tyrosine phosphatase, receptor type, C-associated protein |
| Host | Rabbit |
| Reactivity | human |
| Recommended Dilution | WB: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q14761 |
| Alias | LPAP,CD45-AP,PTPRCAP,CD45-associated protein,Lymphocyte phosphatase-associated phosphoprotein,PTPRC-associated protein,Protein tyrosine phosphatase receptor type C-associated protein |
| Background | Antibody anti-PTPRCAP |
| Status | RUO |
| Note | This product is for research use only. |
Protein Tyrosine Phosphatase Receptor Type C Associated Protein (PTPRCAP), also known as CD45-associated protein, is a regulatory component of the CD45 phosphatase complex. CD45 is a transmembrane protein tyrosine phosphatase expressed on all nucleated hematopoietic cells and is essential for T-cell receptor (TCR) and B-cell receptor (BCR) signaling. PTPRCAP modulates CD45 activity, influencing immune cell activation, proliferation, and differentiation. It contributes to the regulation of lymphocyte signaling thresholds, thereby impacting immune responses and tolerance. Alterations in PTPRCAP expression or function are implicated in immune-related disorders, including autoimmunity and immunodeficiency. The protein plays a role in maintaining immune homeostasis and is a subject of interest for therapeutic interventions targeting immune dysregulation. Further studies are needed to clarify its precise mechanisms and broader biological roles in immune signaling.
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