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The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Primary Antibodies
polyclonal
human,mouse,rat
prostaglandin D2 synthase 21kDa (brain)
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC
33 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
PTGDS
L-PGDS,LPGDS,PDS,PGD2,PGDS,PGDS2,Beta-trace protein,Glutathione-independent PGD synthase
This product is for research use only.
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