PTBP2 antibody
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Description
RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | polypyrimidine tract binding protein 2 (PTBP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 57-60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UKA9 |
| Gene ID | 58155 |
| Alias | Polypyrimidine tract-binding protein 2,Neural polypyrimidine tract-binding protein,Neurally-enriched homolog of PTB,PTB-like protein,PTBP2,NPTB,PTB,PTBLP |
| Background | Antibody anti-PTBP2 |
| Status | RUO |
| Note | Mol. Weight 57-60 kDa |
Descripción
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