PSMC4 antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory(or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | proteasome(prosome, macropain) 26S subunit, ATPase, 4 (PSMC4) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 47 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P43686 |
Gene ID | 5704 |
Alias | 26S proteasome regulatory subunit 6B,26S proteasome AAA-ATPase subunit RPT3,MB67-interacting protein,MIP224,Proteasome 26S subunit ATPase 4,Tat-binding protein 7 (TBP-7),PSMC4,MIP224,TBP7 |
Background | Antibody anti-PSMC4 |
Status | RUO |
Note | Mol. Weight 47 kDa |
Descripción
Related Products

PSMC4 antibody
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory(or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
Ver Producto
26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody
26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody is a Rabbit Polyclonal antibody against 26S Proteasome Regulatory Subunit 6B (PSMC4). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Ver Producto
Human 26S Proteasome Regulatory Subunit 6B (PSMC4) Protein
Recombinant 26S Proteasome Regulatory Subunit 6B (PSMC4) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Ver Producto