PRPF8 antibody

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Description
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | PRP8 pre-mRNA processing factor 8 homolog (PRPF8) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:1000; IHC: 1:50 - 1:100 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 274 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q6P2Q9 |
Gene ID | 10594 |
Alias | Pre-mRNA-processing-splicing factor 8,220 kDa U5 snRNP-specific protein,PRP8 homolog,Splicing factor Prp8,p220,PRPF8,PRPC8 |
Background | Antibody anti-PRPF8 |
Status | RUO |
Note | Mol. Weight 274 kDa |
Descripción
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