PRMT5 antibody
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Description
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein arginine methyltransferase 5 (PRMT5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat, Monkey |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O14744 |
| Gene ID | 10419 |
| Alias | Protein arginine N-methyltransferase 5 (PRMT5),72 kDa ICln-binding protein,Histone-arginine N-methyltransferase PRMT5,Jak-binding protein 1,Shk1 kinase-binding protein 1 homolog (SKB1 homolog, SKB1Hs),Protein arginine N-methyltransferase 5, N-terminally processed,PRMT5,HRMT1L5,IBP72,JBP1,SKB1 |
| Background | Antibody anti-PRMT5 |
| Status | RUO |
| Note | Mol. Weight 70 kDa |
Descripción
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