PPP6C antibody

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935106861
info@markelab.com
name
PPP6C antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06736
tested applications
ELISA, WB

Description

Catalytic subunit of protein phosphatase 6(PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
protein phosphatase 6, catalytic subunit (PPP6C)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
35 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O00743
Gene ID
5537
Alias
Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C),Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed,PPP6C,PPP6
Background
Antibody anti-PPP6C
Status
RUO
Note
Mol. Weight 35 kDa

Descripción

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PPP6C antibody

Catalytic subunit of protein phosphatase 6(PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

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