PPP2R1B antibody
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Description
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform (PPP2R1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 65 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P30154 |
| Gene ID | 5519 |
| Alias | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform,PP2A subunit A isoform PR65-beta,PP2A subunit A isoform R1-beta,PPP2R1B |
| Background | Antibody anti-PPP2R1B |
| Status | RUO |
| Note | Mol. Weight 65 kDa |
Descripción
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