PPP1R8 antibody

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Description
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 40 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q12972 |
| Gene ID | 5511 |
| Alias | Nuclear inhibitor of protein phosphatase 1 (NIPP-1),Protein phosphatase 1 regulatory inhibitor subunit 8,PPP1R8,ARD1,NIPP1 |
| Background | Antibody anti-PPP1R8 |
| Status | RUO |
| Note | Mol. Weight 40 kDa |
Descripción
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