PPARGC1B antibody
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Description
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1(NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 100-110 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IP, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q86YN6 |
| Gene ID | 133522 |
| Alias | Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta),PGC-1-related estrogen receptor alpha coactivator,PPARGC1B,PERC,PGC1,PGC1B,PPARGC1 |
| Background | Antibody anti-PPARGC1B |
| Status | RUO |
| Note | Mol. Weight 100-110 kDa |
Descripción
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