PODXL antibody

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935106861
info@markelab.com
name
PODXL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06597
tested applications
ELISA, WB, IHC, FC
Description
Podocalyxin, also known as podocalyxin-like protein 1(PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | podocalyxin (PODXL) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:1000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 59 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, FC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O00592 |
Alias | Podocalyxin,GCTM-2 antigen,Gp200,Podocalyxin-like protein 1 (PC, PCLP-1),PODXL,PCLP,PCLP1 |
Background | Antibody anti-PODXL |
Status | RUO |
Note | Mol. Weight 59 kDa |
Descripción
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PODXL antibody
Podocalyxin, also known as podocalyxin-like protein 1(PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.
Ver Producto