PKMYT1 antibody
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Description
Acts as a negative regulator of entry into mitosis(G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q99640 |
| Gene ID | 9088 |
| Alias | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase,Myt1 kinase,PKMYT1,MYT1 |
| Background | Antibody anti-PKMYT1 |
| Status | RUO |
| Note | Mol. Weight 55 kDa |
Descripción
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