PKD2L1 antibody
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Description
Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | polycystic kidney disease 2-like 1 (PKD2L1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 92 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9P0L9 |
| Gene ID | 9033 |
| Alias | Polycystin-2-like protein 1 (Polycystin-2L1),Polycystic kidney disease 2-like 1 protein,Polycystin-2 homolog,Polycystin-L,Polycystin-L1,PKD2L1,PKD2L,PKDL,TRPP3 |
| Background | Antibody anti-PKD2L1 |
| Status | RUO |
| Note | Mol. Weight 92 kDa |
Descripción
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