PITRM1 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | pitrilysin metallopeptidase 1 (PITRM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 117 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q5JRX3 |
| Gene ID | 10531 |
| Alias | Presequence protease, mitochondrial (hPreP),Pitrilysin metalloproteinase 1 (Metalloprotease 1, hMP1),PITRM1,KIAA1104,MP1,PREP |
| Background | Antibody anti-PITRM1 |
| Status | RUO |
| Note | Mol. Weight 117 kDa |
Descripción
Related Products
PITRM1 antibody
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
Ver Producto
Presequence Protease, Mitochondrial (PITRM1) Antibody
PITRM1 Antibody is a Rabbit Polyclonal Antibody against PITRM1.
Ver Producto
Presequence Protease, Mitochondrial (PITRM1) Antibody
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Ver Producto