PIEZO2 antibody
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Description
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Piezo-type mechanosensitive ion channel component 2 (PIEZO2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1:50-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H5I5 |
| Alias | Piezo-type mechanosensitive ion channel component 2,Protein FAM38B,PIEZO2,C18orf30,C18orf58,FAM38B |
| Background | Antibody anti-PIEZO2 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
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Human PIEZO2(Piezo-type mechanosensitive ion channel component 2) ELISA Kit
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PIEZO2 antibody
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) Antibody
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi, ' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010 [PubMed 20813920]).
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