Phospho-Camk2a (T286) antibody
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Description
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | calcium/calmodulin-dependent protein kinase II alpha (Phospho-Camk2a (T286)) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 54 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UQM7 |
| Alias | Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha, CaMK-II subunit alpha),CAMK2A,CAMKA,KIAA0968 |
| Background | Antibody anti-Camk2a |
| Status | RUO |
| Note | Mol. Weight 54 kDa |
Descripción
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