Phospho-Akt(Ser473) antibody
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935106861
info@markelab.com
name
Phospho-Akt(Ser473) antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06402
tested applications
ELISA, IHC, WB
Description
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | v-akt murine thymoma viral oncogene homolog 1 (Phospho-Akt(Ser473)) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:4000; IHC: 1:50-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 5H4 |
| Observed MW | 60KD |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P31749 |
| Alias | RAC-alpha serine/threonine-protein kinase,Protein kinase B (PKB),Protein kinase B alpha (PKB alpha),Proto-oncogene c-Akt,RAC-PK-alpha,AKT1,PKB,RAC |
| Background | Antibody anti-Akt |
| Status | RUO |
| Note | Mol. Weight 60 kDa |
Descripción
Related Products
Phospho-Akt(Ser473) antibody
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification.
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