PDLIM5 antibody
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Description
May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | PDZ and LIM domain 5 (PDLIM5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 63-68KD |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96HC4 |
| Gene ID | 10611 |
| Alias | PDZ and LIM domain protein 5,Enigma homolog,Enigma-like PDZ and LIM domains protein,PDLIM5,ENH |
| Background | Antibody anti-PDLIM5 |
| Status | RUO |
| Note | Mol. Weight 63-68 kDa |
Descripción
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PDLIM5 antibody
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PDLIM5 Antibody is a Rabbit Polyclonal antibody against PDLIM5. This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants.
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