PDE3B antibody

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935106861
info@markelab.com
name
PDE3B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06252
tested applications
ELISA, IP

Description

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
phosphodiesterase 3B, cGMP-inhibited (PDE3B)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IP: 1:200-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
124 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q13370
Gene ID
5140
Alias
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B,CGIPDE1 (CGIP1),Cyclic GMP-inhibited phosphodiesterase B (CGI-PDE B),PDE3B
Background
Antibody anti-PDE3B
Status
RUO
Note
Mol. Weight 124 kDa

Descripción

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