PCSK7 antibody
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Description
Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | proprotein convertase subtilisin/kexin type 7 (PCSK7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 68KD |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q16549 |
| Gene ID | 9159 |
| Alias | Proprotein convertase subtilisin/kexin type 7,Lymphoma proprotein convertase,Prohormone convertase 7,Proprotein convertase 7 (PC7),Proprotein convertase 8 (PC8, hPC8),Subtilisin/kexin-like protease PC7,PCSK7,LPC,PC7,PC8,SPC7 |
| Background | Antibody anti-PCSK7 |
| Status | RUO |
| Note | Mol. Weight 68 kDa |
Descripción
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Human PCSK7 (Proprotein convertase subtilisin/kexin type 7) ELISA Kit
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PCSK7 antibody
Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif.
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Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Antibody
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.
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