PCSK2 antibody
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Description
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | proprotein convertase subtilisin/kexin type 2 (PCSK2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 71KD |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P16519 |
| Gene ID | 5126 |
| Alias | Neuroendocrine convertase 2 (NEC 2),KEX2-like endoprotease 2,Prohormone convertase 2,Proprotein convertase 2 (PC2),PCSK2,NEC2 |
| Background | Antibody anti-PCSK2 |
| Status | RUO |
| Note | Mol. Weight 71 kDa |
Descripción
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PCSK2 antibody
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.
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PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.
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