TENT4B antibody

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Description
Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | PAP associated domain containing 5 (TENT4B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa, 80 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8NDF8 |
| Gene ID | 64282 |
| Alias | Terminal nucleotidyltransferase 4B,Non-canonical poly(A) RNA polymerase PAPD5,PAP-associated domain-containing protein 5,Terminal guanylyltransferase,Terminal uridylyltransferase 3 (TUTase 3),Topoisomerase-related function protein 4-2 (TRF4-2),TENT4B,GLD4,PAPD5,TRF4-2,TUT3 |
| Background | Antibody anti-TENT4B |
| Status | RUO |
| Note | Mol. Weight 50 kDa, 80 kDa |
Descripción
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