PACSIN3 antibody
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Description
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein kinase C and casein kinase substrate in neurons 3 (PACSIN3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 48 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, FC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UKS6 |
| Gene ID | 29763 |
| Alias | Protein kinase C and casein kinase substrate in neurons protein 3,SH3 domain-containing protein 6511,PACSIN3 |
| Background | Antibody anti-PACSIN3 |
| Status | RUO |
| Note | Mol. Weight 48 kDa |
Descripción
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