PACSIN2 antibody
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935106861
info@markelab.com
name
PACSIN2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06101
tested applications
ELISA, IHC, WB, IP
Description
Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein kinase C and casein kinase substrate in neurons 2 (PACSIN2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60-65 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UNF0 |
| Gene ID | 11252 |
| Alias | Protein kinase C and casein kinase substrate in neurons protein 2,Syndapin-2,Syndapin-II (SdpII),PACSIN2 |
| Background | Antibody anti-PACSIN2 |
| Status | RUO |
| Note | Mol. Weight 60-65 kDa |
Descripción
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