RPS6KB1 antibody
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Description
RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 65 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P23443 |
| Gene ID | 6198 |
| Alias | Ribosomal protein S6 kinase beta-1 (S6K-beta-1, S6K1),70 kDa ribosomal protein S6 kinase 1 (P70S6K1, p70-S6K 1),Ribosomal protein S6 kinase I,Serine/threonine-protein kinase 14A,p70 ribosomal S6 kinase alpha (p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA),RPS6KB1,STK14A |
| Background | Antibody anti-RPS6KB1 |
| Status | RUO |
| Note | Mol. Weight 65-70 kDa |
Descripción
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RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation.
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