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Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Alpha-1-Acid Glycoprotein (ORM1), also known as orosomucoid, is an acute-phase plasma protein predominantly synthesized in the liver. ORM1 is a part of the acute-phase response, where its levels in the blood increase in response to inflammation, infection, or injury.It is a 43-44 kDa glycoprotein well known as a one of the major acute phase proteins in humans, rats and many other spices The carbohydrate content represents 45% of the molecular weight attached in the form of five to six highly sialylated complex-type-N-linked glycans.ORM1 has since been studied extensively for its role in immune regulation, drug binding, and inflammation.
Primary Antibodies
polyclonal
human,mouse
orosomucoid 1
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC, IP
41-47kd
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
ORM1
Alpha-1-Acid Glycoprotein/orm1,Orosomucoid-1,OMD 1,Orosomucoid 1
This product is for research use only.
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