ORAI1 antibody

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935106861
info@markelab.com
name
ORAI1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06001
tested applications
ELISA, WB, IF

Description

Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 . CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ORAI calcium release-activated calcium modulator 1 (ORAI1)
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Recommended Dilution
WB: 1:500-1:1000; IF: 1:10-1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
45 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q96D31
Gene ID
84876
Alias
Calcium release-activated calcium channel protein 1,Protein orai-1,Transmembrane protein 142A,ORAI1,CRACM1,TMEM142A
Background
Antibody anti-ORAI1
Status
RUO
Note
Mol. Weight 45 kDa

Descripción

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Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 . CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).

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