NUDT3 antibody

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935106861
info@markelab.com
name
NUDT3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05905
tested applications
ELISA, WB

Description

Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5(diphosphoinositol pentakisphosphate) and [PP]2-InsP4(bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6(inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
nudix(nucleoside diphosphate linked moiety X)-type motif 3 (NUDT3)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
20-30kd
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O95989
Gene ID
11165
Alias
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1),Diadenosine hexaphosphate hydrolase (Ap6A hydrolase),Endopolyphosphatase,Nucleoside diphosphate-linked moiety X motif 3 (Nudix motif 3),m7GpppN-mRNA hydrolase,m7GpppX diphosphatase,NUDT3,DIPP,DIPP1
Background
Antibody anti-NUDT3
Status
RUO
Note
Mol. Weight 20-30 kDa

Descripción

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