NUDT3 antibody

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935106861
info@markelab.com
name
NUDT3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05905
tested applications
ELISA, WB
Description
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5(diphosphoinositol pentakisphosphate) and [PP]2-InsP4(bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6(inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | nudix(nucleoside diphosphate linked moiety X)-type motif 3 (NUDT3) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 20-30kd |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O95989 |
Gene ID | 11165 |
Alias | Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1),Diadenosine hexaphosphate hydrolase (Ap6A hydrolase),Endopolyphosphatase,Nucleoside diphosphate-linked moiety X motif 3 (Nudix motif 3),m7GpppN-mRNA hydrolase,m7GpppX diphosphatase,NUDT3,DIPP,DIPP1 |
Background | Antibody anti-NUDT3 |
Status | RUO |
Note | Mol. Weight 20-30 kDa |
Descripción
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NUDT3 antibody
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5(diphosphoinositol pentakisphosphate) and [PP]2-InsP4(bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6(inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Ver Producto